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Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax

BACKGROUND: The subterranean blind mole rat, Spalax (genus Nannospalax) endures extreme hypoxic conditions and fluctuations in oxygen levels that threaten DNA integrity. Nevertheless, Spalax is long-lived, does not develop spontaneous cancer, and exhibits an outstanding resistance to carcinogenesis...

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Detalles Bibliográficos
Autores principales:	Domankevich, Vered, Opatowsky, Yarden, Malik, Assaf, Korol, Abraham B., Frenkel, Zeev, Manov, Irena, Avivi, Aaron, Shams, Imad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010716/ https://www.ncbi.nlm.nih.gov/pubmed/27590526 http://dx.doi.org/10.1186/s12862-016-0743-8

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