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DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years

AIMS: Antisense non-coding RNA in the INK4 locus (ANRIL) fixed genetic variants have consistently been linked with coronary heart disease (CHD) risk. We investigated relationships between perinatal ANRIL promoter DNA methylation and CHD risk markers in children aged 9 years. Genetic variants in the...

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Detalles Bibliográficos
Autores principales: Murray, Robert, Bryant, Jennifer, Titcombe, Phil, Barton, Sheila J., Inskip, Hazel, Harvey, Nicholas C., Cooper, Cyrus, Lillycrop, Karen, Hanson, Mark, Godfrey, Keith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010744/
https://www.ncbi.nlm.nih.gov/pubmed/27594927
http://dx.doi.org/10.1186/s13148-016-0259-5