The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide

BACKGROUND: The toxicity of amyloid-β (Aβ) peptide present in the brain of Alzheimer’s disease (AD) patients is thought to be mediated via the increased secretion of pro-inflammatory mediators, which can lead to neuronal dysfunction and cell death. In addition, we have previously shown that inflamma...

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Detalles Bibliográficos
Autores principales: Ries, Miriam, Loiola, Rodrigo, Shah, Urvi N., Gentleman, Steve M., Solito, Egle, Sastre, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010757/
https://www.ncbi.nlm.nih.gov/pubmed/27590054
http://dx.doi.org/10.1186/s12974-016-0692-6

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