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Subgroup and sensitivity analyses of annualized relapse rate over 2 years in the ADVANCE trial of peginterferon beta-1a in patients with relapsing-remitting multiple sclerosis
ADVANCE was a 2-year, double-blind, placebo-controlled, Phase 3 study in 1512 patients aged 18–65 years with relapsing-remitting multiple sclerosis, which demonstrated that peginterferon beta-1a 125 mcg administered subcutaneously every 2 or 4 weeks led to significant reductions in annualized relaps...
Autores principales: | Newsome, Scott D., Kieseier, Bernd C., Arnold, Douglas L., Shang, Shulian, Liu, Shifang, Hung, Serena, Sabatella, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010838/ https://www.ncbi.nlm.nih.gov/pubmed/27314959 http://dx.doi.org/10.1007/s00415-016-8182-4 |
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