Inhibition of microRNA-21 decreases the invasiveness of fibroblast-like synoviocytes in rheumatoid arthritis via TGF(β)/Smads signaling pathway

OBJECTIVE(S): MicroRNA-21 (miR(21)) is aberrantly elevated in rheumatoid arthritis (RA) patients, the significance of this microRNA in RA pathogenesis and treatment, however, has not been investigated. In this study, by using RA-derived fibroblast-like synoviocyte (FLS) cells as a model, we investig...

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Detalles Bibliográficos
Autores principales: Xiong, Gaoxin, Huang, Zhang, Jiang, Hua, Pan, Zhengjun, Xie, Jie, Wang, Shuangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010852/
https://www.ncbi.nlm.nih.gov/pubmed/27635204

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