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Concurrence of High Fat Diet and APOE Gene Induces Allele Specific Metabolic and Mental Stress Changes in a Mouse Model of Alzheimer’s Disease

Aging is the main risk factor for neurodegenerative diseases, including Alzheimer’s disease (AD). However, evidence indicates that the pathological process begins long before actual cognitive or pathological symptoms are apparent. The long asymptomatic phase and complex integration between genetic,...

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Detalles Bibliográficos
Autores principales: Segev, Yifat, Livne, Adva, Mints, Meshi, Rosenblum, Kobi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011130/
https://www.ncbi.nlm.nih.gov/pubmed/27656136
http://dx.doi.org/10.3389/fnbeh.2016.00170