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Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report

INTRODUCTION: Due to the complexity of the surgical procedure portal vein thrombosis (PVT) has long been considered an absolute contraindication to liver transplantation (LT). The presence of a large splenorenal shunt (SRS) could make portal anastomosis a valid option. PRESENTATION OF CASE: We repor...

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Autores principales: Manzia, Tommaso Maria, Fazzolari, Laura, Manuelli, Matteo, Pellicciaro, Marco, Baiocchi, Leonardo, Tisone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011162/
https://www.ncbi.nlm.nih.gov/pubmed/27625785
http://dx.doi.org/10.1016/j.amsu.2016.08.002
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author Manzia, Tommaso Maria
Fazzolari, Laura
Manuelli, Matteo
Pellicciaro, Marco
Baiocchi, Leonardo
Tisone, Giuseppe
author_facet Manzia, Tommaso Maria
Fazzolari, Laura
Manuelli, Matteo
Pellicciaro, Marco
Baiocchi, Leonardo
Tisone, Giuseppe
author_sort Manzia, Tommaso Maria
collection PubMed
description INTRODUCTION: Due to the complexity of the surgical procedure portal vein thrombosis (PVT) has long been considered an absolute contraindication to liver transplantation (LT). The presence of a large splenorenal shunt (SRS) could make portal anastomosis a valid option. PRESENTATION OF CASE: We report the case of a 37-year-old female patient with Grade III PVT and a large SRS, who underwent orthotopic LT. Liver was implanted using a 1992-Belghiti piggyback technique and portal anastomosis was performed using the large spleno-renal shunt. We observed good graft reperfusion and postoperative Doppler ultrasound showed normal portal vein flow. She was discharged on postoperative day 7, with an excellent graft function. At six months follow-up, patient is alive with normal hepatic vascularization. DISCUSSION: Due to paucity of reports, there is currently no consensus on the indication to LT and/or surgical technique. In the present case, once the transplant benefit was evaluated, the Grade III PVT was not considered a contraindication to LT. CONCLUSION: The presence of a Grade III PVT associated with a large SRS should not be considered a contraindication for LT, and the use of the shunt vein should be considered a feasible option to perform portal anastomosis.
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spelling pubmed-50111622016-09-13 Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report Manzia, Tommaso Maria Fazzolari, Laura Manuelli, Matteo Pellicciaro, Marco Baiocchi, Leonardo Tisone, Giuseppe Ann Med Surg (Lond) Case Report INTRODUCTION: Due to the complexity of the surgical procedure portal vein thrombosis (PVT) has long been considered an absolute contraindication to liver transplantation (LT). The presence of a large splenorenal shunt (SRS) could make portal anastomosis a valid option. PRESENTATION OF CASE: We report the case of a 37-year-old female patient with Grade III PVT and a large SRS, who underwent orthotopic LT. Liver was implanted using a 1992-Belghiti piggyback technique and portal anastomosis was performed using the large spleno-renal shunt. We observed good graft reperfusion and postoperative Doppler ultrasound showed normal portal vein flow. She was discharged on postoperative day 7, with an excellent graft function. At six months follow-up, patient is alive with normal hepatic vascularization. DISCUSSION: Due to paucity of reports, there is currently no consensus on the indication to LT and/or surgical technique. In the present case, once the transplant benefit was evaluated, the Grade III PVT was not considered a contraindication to LT. CONCLUSION: The presence of a Grade III PVT associated with a large SRS should not be considered a contraindication for LT, and the use of the shunt vein should be considered a feasible option to perform portal anastomosis. Elsevier 2016-08-19 /pmc/articles/PMC5011162/ /pubmed/27625785 http://dx.doi.org/10.1016/j.amsu.2016.08.002 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Manzia, Tommaso Maria
Fazzolari, Laura
Manuelli, Matteo
Pellicciaro, Marco
Baiocchi, Leonardo
Tisone, Giuseppe
Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
title Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
title_full Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
title_fullStr Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
title_full_unstemmed Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
title_short Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
title_sort liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011162/
https://www.ncbi.nlm.nih.gov/pubmed/27625785
http://dx.doi.org/10.1016/j.amsu.2016.08.002
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