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Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report
INTRODUCTION: Due to the complexity of the surgical procedure portal vein thrombosis (PVT) has long been considered an absolute contraindication to liver transplantation (LT). The presence of a large splenorenal shunt (SRS) could make portal anastomosis a valid option. PRESENTATION OF CASE: We repor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011162/ https://www.ncbi.nlm.nih.gov/pubmed/27625785 http://dx.doi.org/10.1016/j.amsu.2016.08.002 |
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author | Manzia, Tommaso Maria Fazzolari, Laura Manuelli, Matteo Pellicciaro, Marco Baiocchi, Leonardo Tisone, Giuseppe |
author_facet | Manzia, Tommaso Maria Fazzolari, Laura Manuelli, Matteo Pellicciaro, Marco Baiocchi, Leonardo Tisone, Giuseppe |
author_sort | Manzia, Tommaso Maria |
collection | PubMed |
description | INTRODUCTION: Due to the complexity of the surgical procedure portal vein thrombosis (PVT) has long been considered an absolute contraindication to liver transplantation (LT). The presence of a large splenorenal shunt (SRS) could make portal anastomosis a valid option. PRESENTATION OF CASE: We report the case of a 37-year-old female patient with Grade III PVT and a large SRS, who underwent orthotopic LT. Liver was implanted using a 1992-Belghiti piggyback technique and portal anastomosis was performed using the large spleno-renal shunt. We observed good graft reperfusion and postoperative Doppler ultrasound showed normal portal vein flow. She was discharged on postoperative day 7, with an excellent graft function. At six months follow-up, patient is alive with normal hepatic vascularization. DISCUSSION: Due to paucity of reports, there is currently no consensus on the indication to LT and/or surgical technique. In the present case, once the transplant benefit was evaluated, the Grade III PVT was not considered a contraindication to LT. CONCLUSION: The presence of a Grade III PVT associated with a large SRS should not be considered a contraindication for LT, and the use of the shunt vein should be considered a feasible option to perform portal anastomosis. |
format | Online Article Text |
id | pubmed-5011162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-50111622016-09-13 Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report Manzia, Tommaso Maria Fazzolari, Laura Manuelli, Matteo Pellicciaro, Marco Baiocchi, Leonardo Tisone, Giuseppe Ann Med Surg (Lond) Case Report INTRODUCTION: Due to the complexity of the surgical procedure portal vein thrombosis (PVT) has long been considered an absolute contraindication to liver transplantation (LT). The presence of a large splenorenal shunt (SRS) could make portal anastomosis a valid option. PRESENTATION OF CASE: We report the case of a 37-year-old female patient with Grade III PVT and a large SRS, who underwent orthotopic LT. Liver was implanted using a 1992-Belghiti piggyback technique and portal anastomosis was performed using the large spleno-renal shunt. We observed good graft reperfusion and postoperative Doppler ultrasound showed normal portal vein flow. She was discharged on postoperative day 7, with an excellent graft function. At six months follow-up, patient is alive with normal hepatic vascularization. DISCUSSION: Due to paucity of reports, there is currently no consensus on the indication to LT and/or surgical technique. In the present case, once the transplant benefit was evaluated, the Grade III PVT was not considered a contraindication to LT. CONCLUSION: The presence of a Grade III PVT associated with a large SRS should not be considered a contraindication for LT, and the use of the shunt vein should be considered a feasible option to perform portal anastomosis. Elsevier 2016-08-19 /pmc/articles/PMC5011162/ /pubmed/27625785 http://dx.doi.org/10.1016/j.amsu.2016.08.002 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Manzia, Tommaso Maria Fazzolari, Laura Manuelli, Matteo Pellicciaro, Marco Baiocchi, Leonardo Tisone, Giuseppe Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report |
title | Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report |
title_full | Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report |
title_fullStr | Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report |
title_full_unstemmed | Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report |
title_short | Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report |
title_sort | liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011162/ https://www.ncbi.nlm.nih.gov/pubmed/27625785 http://dx.doi.org/10.1016/j.amsu.2016.08.002 |
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