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Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster

Exposure to organophosphate compounds, such as chlorpyrifos, has been linked to disturbances on cell signaling pathways. Mitogen activated protein kinases (MAPK) are a family of protein kinases involved in a range of cellular processes, including stress response, apoptosis and survival. Therefore, c...

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Detalles Bibliográficos
Autores principales: Batista, J.E.S., Sousa, L.R., Martins, I.K., Rodrigues, N.R., Posser, T., Franco, J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011164/
https://www.ncbi.nlm.nih.gov/pubmed/27626050
http://dx.doi.org/10.1016/j.dib.2016.08.033
Descripción
Sumario:Exposure to organophosphate compounds, such as chlorpyrifos, has been linked to disturbances on cell signaling pathways. Mitogen activated protein kinases (MAPK) are a family of protein kinases involved in a range of cellular processes, including stress response, apoptosis and survival. Therefore, changes in the activation state of these kinases may characterize key mechanisms of toxicity elicited by xenobiotics. Here we report data on the phosphorylation of p38MAPK and JNK, members of the MAPK family, in Drosophila melanogaster exposed to chlorpyrifos, as characterized by western blotting assays.