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The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo studies
Studying rats fed high cholesterol diet and a pancreatic β-cell line (Min6), we aimed to determine the mechanisms by which quercetin protects against cholesterol-induced pancreatic β-cell dysfunction and impairments in glycemic control. Quercetin prevented the increase in total plasma cholesterol, b...
Autores principales: | Carrasco-Pozo, Catalina, Tan, Kah Ni, Reyes-Farias, Marjorie, De La Jara, Nicole, Ngo, Shyuan Thieu, Garcia-Diaz, Diego Fernando, Llanos, Paola, Cires, Maria Jose, Borges, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011185/ https://www.ncbi.nlm.nih.gov/pubmed/27591402 http://dx.doi.org/10.1016/j.redox.2016.08.007 |
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