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Antibody to FcεRIα Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation

PURPOSE: High-affinity receptor I (FcεRI) on mast cells and basophils plays a key role in the immunoglobulin E (IgE)-mediated type I hypersensitivity mediated by allergen cross-linking of the specific IgE-FcεRI complex. Thus, prevention of IgE binding to FcεRI on these cells is an effective therapy...

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Detalles Bibliográficos
Autores principales:	Hong, Jung Yeon, Bae, Jong-Hwan, Lee, Kyung Eun, Kim, Mina, Kim, Min Hee, Kang, Hyun Jung, Park, Eun Hye, Yoo, Kyung Sook, Jeong, Se Kyoo, Kim, Kyung Won, Kim, Kyu-Earn, Sohn, Myung Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011273/ https://www.ncbi.nlm.nih.gov/pubmed/27593869 http://dx.doi.org/10.3349/ymj.2016.57.6.1412

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