AC‐1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model

Antibody‐derived peptides modulate functions of the immune system and are a source of anti‐infective and antitumor substances. Recent studies have shown that they comprise amino acid sequences of immunoglobulin complementarity‐determining regions, but also fragments of constant regions. V(H) CDR3 of...

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Detalles Bibliográficos
Autores principales: Rabaça, Aline N., Arruda, Denise C., Figueiredo, Carlos R., Massaoka, Mariana H., Farias, Camyla F., Tada, Dayane B., Maia, Vera C., Silva Junior, Pedro I., Girola, Natalia, Real, Fernando, Mortara, Renato A., Polonelli, Luciano, Travassos, Luiz R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011487/
https://www.ncbi.nlm.nih.gov/pubmed/27642552
http://dx.doi.org/10.1002/2211-5463.12080

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