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Mice with a heterozygous Lrp6 deletion have impaired fracture healing
Bone fracture non-unions, the failure of a fracture to heal, occur in 10%–20% of fractures and are a costly and debilitating clinical problem. The Wnt/β-catenin pathway is critical in bone development and fracture healing. Polymorphisms of linking low-density lipoprotein receptor-related protein 6 (...
Autores principales: | Burgers, Travis A, Vivanco, Juan F, Zahatnansky, Juraj, Moren, Andrew J Vander, Mason, James J, Williams, Bart O |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011612/ https://www.ncbi.nlm.nih.gov/pubmed/27635281 http://dx.doi.org/10.1038/boneres.2016.25 |
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