Bivalent Copper Ions Promote Fibrillar Aggregation of KCTD1 and Induce Cytotoxicity

Potassium channel tetramerization domain containing 1 (KCTD1) family members have a BTB/POZ domain, which can facilitate protein-protein interactions involved in the regulation of different signaling pathways. KCTD proteins have potential Zn(2+)/Cu(2+) binding sites with currently unknown structural...

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Detalles Bibliográficos
Autores principales: Liu, Zhepeng, Song, Feifei, Ma, Zhi-li, Xiong, Qiushuang, Wang, Jingwen, Guo, Deyin, Sun, Guihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011690/
https://www.ncbi.nlm.nih.gov/pubmed/27596723
http://dx.doi.org/10.1038/srep32658

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