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State-dependent diffusion of actin-depolymerizing factor/cofilin underlies the enlargement and shrinkage of dendritic spines

Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain, and spine enlargement and shrinkage give rise to long-term potentiation and depression of synapses, respectively. Because spine structural plasticity is accompanied by remodeling of actin scaffolds, we hypothesized...

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Detalles Bibliográficos
Autores principales: Noguchi, Jun, Hayama, Tatsuya, Watanabe, Satoshi, Ucar, Hasan, Yagishita, Sho, Takahashi, Noriko, Kasai, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011767/
https://www.ncbi.nlm.nih.gov/pubmed/27595610
http://dx.doi.org/10.1038/srep32897