MiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells

BACKGROUND: In ovarian cancer (OC) cells, Snail was reported to induce the epithelial-to-mesenchymal transition (EMT), which is a critical step in OC metastasis. At present little is known about controlling Snail expression in OC cells by using specific microRNAs (miRNAs). METHODS: We first used a c...

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Detalles Bibliográficos
Autores principales: Dong, Peixin, Xiong, Ying, Watari, Hidemichi, Hanley, Sharon J. B., Konno, Yosuke, Ihira, Kei, Yamada, Takahiro, Kudo, Masataka, Yue, Junming, Sakuragi, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011787/
https://www.ncbi.nlm.nih.gov/pubmed/27596137
http://dx.doi.org/10.1186/s13046-016-0415-y

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