CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)

BACKGROUND: Loss of Amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase (AGL) drives rapid proliferation of bladder cancer cells by upregulating Hyaluronic acid(HA) Synthase (HAS2) mediated HA synthesis. However the role of HA receptors CD44 and Hyaluronan Mediated Motility Receptor (RHAMM) in re...

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Detalles Bibliográficos
Autores principales: Oldenburg, Darby, Ru, Yuanbin, Weinhaus, Benjamin, Cash, Steve, Theodorescu, Dan, Guin, Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011830/
https://www.ncbi.nlm.nih.gov/pubmed/27595989
http://dx.doi.org/10.1186/s12885-016-2756-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011830/
https://www.ncbi.nlm.nih.gov/pubmed/27595989
http://dx.doi.org/10.1186/s12885-016-2756-5

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