Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway

BACKGROUND: Recent studies indicated that histone deacetylase inhibitors (HDACi), a class of anticancer agents, are in addition to their ability of apoptosis induction also capable of provoking autophagy. Promoted by the treatment of malignant uterine sarcoma cells with the HDACi suberoylanilide hyd...

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Detalles Bibliográficos
Autores principales: Fröhlich, Leopold F., Mrakovcic, Maria, Smole, Claudia, Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011867/
https://www.ncbi.nlm.nih.gov/pubmed/27601937
http://dx.doi.org/10.1186/s12935-016-0343-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011867/
https://www.ncbi.nlm.nih.gov/pubmed/27601937
http://dx.doi.org/10.1186/s12935-016-0343-0

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