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Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway
BACKGROUND: Recent studies indicated that histone deacetylase inhibitors (HDACi), a class of anticancer agents, are in addition to their ability of apoptosis induction also capable of provoking autophagy. Promoted by the treatment of malignant uterine sarcoma cells with the HDACi suberoylanilide hyd...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011867/ https://www.ncbi.nlm.nih.gov/pubmed/27601937 http://dx.doi.org/10.1186/s12935-016-0343-0 |