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MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes

Keloid is the abnormal wound healing puzzled by the aggressive growth and high recurrence rate due to its unrevealed key pathogenic mechanism. MicroRNAs contribute to a series of biological processes including epithelial-mesenchymal transition (EMT) and cells stemness involved in fibrotic disease. H...

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Detalles Bibliográficos
Autores principales: Yan, Li, Cao, Rui, Liu, YuanBo, Wang, LianZhao, Pan, Bo, Lv, XiaoYan, Jiao, Hu, Zhuang, Qiang, Sun, XueJian, Xiao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011940/
https://www.ncbi.nlm.nih.gov/pubmed/27596120
http://dx.doi.org/10.1038/srep28281