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Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease

Demyelination underlies early neurological symptoms in multiple sclerosis (MS); however, axonal damage is considered critical for permanent chronic deficits. The precise mechanisms by which axonal injury occurs in MS are unclear; one hypothesis is the absence or failure of remyelination, suggesting...

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Detalles Bibliográficos
Autores principales: Wootla, Bharath, Denic, Aleksandar, Watzlawik, Jens O., Warrington, Arthur E., Rodriguez, Moses
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012151/
https://www.ncbi.nlm.nih.gov/pubmed/26409478
http://dx.doi.org/10.1007/s12035-015-9436-3