APOL1 Risk Alleles Are Associated With More Severe Arteriosclerosis in Renal Resistance Vessels With Aging and Hypertension

INTRODUCTION: The increased risk of end-stage kidney disease among hypertensive African Americans is partly related to APOL1 allele variants. The initial glomerulosclerosis of hypertension-associated arterionephrosclerosis consists of focal global glomerulosclerosis, but in biopsy studies, focal seg...

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Detalles Bibliográficos
Autores principales: Hughson, Michael D., Hoy, Wendy E., Mott, Susan A., Puelles, Victor G., Bertram, John F., Winkler, Cheryl A., Kopp, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012291/
https://www.ncbi.nlm.nih.gov/pubmed/27610422
http://dx.doi.org/10.1016/j.ekir.2016.03.002

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