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Gene expression variability in mammalian embryonic stem cells using single cell RNA-seq data

BACKGROUND: Gene expression heterogeneity contributes to development as well as disease progression. Due to technological limitations, most studies to date have focused on differences in mean expression across experimental conditions, rather than differences in gene expression variance. The advent o...

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Detalles Bibliográficos
Autores principales: Mantsoki, Anna, Devailly, Guillaume, Joshi, Anagha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012374/
https://www.ncbi.nlm.nih.gov/pubmed/26951854
http://dx.doi.org/10.1016/j.compbiolchem.2016.02.004

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