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Single Molecule Studies of the Diffusion of Band 3 in Sickle Cell Erythrocytes

Sickle cell disease (SCD) is caused by an inherited mutation in hemoglobin that leads to sickle hemoglobin (HbS) polymerization and premature HbS denaturation. Previous publications have shown that HbS denaturation is followed by binding of denatured HbS (a.k.a. hemichromes) to band 3, the consequen...

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Detalles Bibliográficos
Autores principales:	Spector, Jeff, Kodippili, Gayani C., Ritchie, Ken, Low, Philip S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012561/ https://www.ncbi.nlm.nih.gov/pubmed/27598991 http://dx.doi.org/10.1371/journal.pone.0162514

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