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Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production

Microglial priming and enhanced reactivity to secondary insults cause substantial neuronal damage and are hallmarks of brain aging, traumatic brain injury and neurodegenerative diseases. It is, thus, of particular interest to identify mechanisms involved in microglial priming. Here, we demonstrate t...

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Detalles Bibliográficos
Autores principales: Spencer, Nicholas G., Schilling, Tom, Miralles, Francesc, Eder, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012572/
https://www.ncbi.nlm.nih.gov/pubmed/27598576
http://dx.doi.org/10.1371/journal.pone.0162497