Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies

Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the dysregulation of the epithelial barrier. New therapeutic...

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Detalles Bibliográficos
Autores principales: Randall, Kevin, Henderson, Neil, Reens, Jaimini, Eckersley, Sonia, Nyström, Ann-Christin, South, Marie C., Balendran, Clare A., Böttcher, Gerhard, Hughes, Glen, Price, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012586/
https://www.ncbi.nlm.nih.gov/pubmed/27598247
http://dx.doi.org/10.1371/journal.pone.0162076

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