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IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

Pneumococcal lung infections represent a major cause of death worldwide. Single nucleotide polymorphisms (SNPs) in the NFKBIZ gene, encoding the transcription factor IκBζ, are associated with increased susceptibility to invasive pneumococcal disease. We hence analyzed how IκBζ might regulate inflamm...

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Detalles Bibliográficos
Autores principales: Sundaram, Kruthika, Rahman, Mohd. Akhlakur, Mitra, Srabani, Knoell, Daren L., Woodiga, Shireen A., King, Samantha J., Wewers, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012667/
https://www.ncbi.nlm.nih.gov/pubmed/27597997
http://dx.doi.org/10.1371/journal.pone.0161931

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