Limited Generalizability of Registration Trials in Hepatitis C: A Nationwide Cohort Study

BACKGROUND: Approval of drugs in chronic hepatitis C is supported by registration trials. These trials might have limited generalizability through use of strict eligibility criteria. We compared effectiveness and safety of real world hepatitis C patients eligible and ineligible for registration tria...

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Detalles Bibliográficos
Autores principales: Berden, Floor A. C., de Knegt, Robert J., Blokzijl, Hans, Kuiken, Sjoerd D., van Erpecum, Karel J. L., Willemse, Sophie B., den Hollander, Jan, van Vonderen, Marit G. A., Friederich, Pieter, van Hoek, Bart, van Nieuwkerk, Carin M. J., Drenth, Joost P. H., Kievit, Wietske
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012685/
https://www.ncbi.nlm.nih.gov/pubmed/27598789
http://dx.doi.org/10.1371/journal.pone.0161821

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