Cargando…
Surgical management for squamous cell carcinoma of vulva
To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analys...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012828/ https://www.ncbi.nlm.nih.gov/pubmed/27642483 http://dx.doi.org/10.11604/pamj.2016.24.145.8485 |
_version_ | 1782452061101621248 |
---|---|
author | Amavi, Ayi Kossigan Kouadio, Laurent Adabra, Komlan Tengue, Kodjo Tijami, Fouad Jalil, Abdelouahed |
author_facet | Amavi, Ayi Kossigan Kouadio, Laurent Adabra, Komlan Tengue, Kodjo Tijami, Fouad Jalil, Abdelouahed |
author_sort | Amavi, Ayi Kossigan |
collection | PubMed |
description | To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N(-) vs 46.7%N(+); p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions. |
format | Online Article Text |
id | pubmed-5012828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-50128282016-09-16 Surgical management for squamous cell carcinoma of vulva Amavi, Ayi Kossigan Kouadio, Laurent Adabra, Komlan Tengue, Kodjo Tijami, Fouad Jalil, Abdelouahed Pan Afr Med J Case Series To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N(-) vs 46.7%N(+); p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions. The African Field Epidemiology Network 2016-06-15 /pmc/articles/PMC5012828/ /pubmed/27642483 http://dx.doi.org/10.11604/pamj.2016.24.145.8485 Text en © Ayi Kossigan Amavi et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Amavi, Ayi Kossigan Kouadio, Laurent Adabra, Komlan Tengue, Kodjo Tijami, Fouad Jalil, Abdelouahed Surgical management for squamous cell carcinoma of vulva |
title | Surgical management for squamous cell carcinoma of vulva |
title_full | Surgical management for squamous cell carcinoma of vulva |
title_fullStr | Surgical management for squamous cell carcinoma of vulva |
title_full_unstemmed | Surgical management for squamous cell carcinoma of vulva |
title_short | Surgical management for squamous cell carcinoma of vulva |
title_sort | surgical management for squamous cell carcinoma of vulva |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012828/ https://www.ncbi.nlm.nih.gov/pubmed/27642483 http://dx.doi.org/10.11604/pamj.2016.24.145.8485 |
work_keys_str_mv | AT amaviayikossigan surgicalmanagementforsquamouscellcarcinomaofvulva AT kouadiolaurent surgicalmanagementforsquamouscellcarcinomaofvulva AT adabrakomlan surgicalmanagementforsquamouscellcarcinomaofvulva AT tenguekodjo surgicalmanagementforsquamouscellcarcinomaofvulva AT tijamifouad surgicalmanagementforsquamouscellcarcinomaofvulva AT jalilabdelouahed surgicalmanagementforsquamouscellcarcinomaofvulva |