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Surgical management for squamous cell carcinoma of vulva

To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analys...

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Autores principales: Amavi, Ayi Kossigan, Kouadio, Laurent, Adabra, Komlan, Tengue, Kodjo, Tijami, Fouad, Jalil, Abdelouahed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012828/
https://www.ncbi.nlm.nih.gov/pubmed/27642483
http://dx.doi.org/10.11604/pamj.2016.24.145.8485
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author Amavi, Ayi Kossigan
Kouadio, Laurent
Adabra, Komlan
Tengue, Kodjo
Tijami, Fouad
Jalil, Abdelouahed
author_facet Amavi, Ayi Kossigan
Kouadio, Laurent
Adabra, Komlan
Tengue, Kodjo
Tijami, Fouad
Jalil, Abdelouahed
author_sort Amavi, Ayi Kossigan
collection PubMed
description To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N(-) vs 46.7%N(+); p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions.
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spelling pubmed-50128282016-09-16 Surgical management for squamous cell carcinoma of vulva Amavi, Ayi Kossigan Kouadio, Laurent Adabra, Komlan Tengue, Kodjo Tijami, Fouad Jalil, Abdelouahed Pan Afr Med J Case Series To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N(-) vs 46.7%N(+); p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions. The African Field Epidemiology Network 2016-06-15 /pmc/articles/PMC5012828/ /pubmed/27642483 http://dx.doi.org/10.11604/pamj.2016.24.145.8485 Text en © Ayi Kossigan Amavi et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Amavi, Ayi Kossigan
Kouadio, Laurent
Adabra, Komlan
Tengue, Kodjo
Tijami, Fouad
Jalil, Abdelouahed
Surgical management for squamous cell carcinoma of vulva
title Surgical management for squamous cell carcinoma of vulva
title_full Surgical management for squamous cell carcinoma of vulva
title_fullStr Surgical management for squamous cell carcinoma of vulva
title_full_unstemmed Surgical management for squamous cell carcinoma of vulva
title_short Surgical management for squamous cell carcinoma of vulva
title_sort surgical management for squamous cell carcinoma of vulva
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012828/
https://www.ncbi.nlm.nih.gov/pubmed/27642483
http://dx.doi.org/10.11604/pamj.2016.24.145.8485
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