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Involvement of NRF2 Signaling in Doxorubicin Resistance of Cancer Stem Cell-Enriched Colonospheres

Cancer stem cells (CSCs) are a subset of tumor cells, which are characterized by resistance against chemotherapy and environmental stress, and are known to cause tumor relapse after therapy. A number of molecular mechanisms underlie the chemoresistance of CSCs, including high expression levels of dr...

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Detalles Bibliográficos
Autores principales: Ryoo, In-geun, Kim, Geon, Choi, Bo-hyun, Lee, Sang-hwan, Kwak, Mi-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012872/
https://www.ncbi.nlm.nih.gov/pubmed/27582554
http://dx.doi.org/10.4062/biomolther.2016.145