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Shikonin Induces Apoptotic Cell Death via Regulation of p53 and Nrf2 in AGS Human Stomach Carcinoma Cells

Shikonin, which derives from Lithospermum erythrorhizon, has been traditionally used against a variety of diseases, including cancer, in Eastern Asia. Here we determined that shikonin inhibits proliferation of gastric cancer cells by inducing apoptosis. Shikonin’s biological activity was validated b...

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Detalles Bibliográficos
Autores principales:	Ko, Hyeonseok, Kim, Sun-Joong, Shim, So Hee, Chang, HyoIhl, Ha, Chang Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012875/ https://www.ncbi.nlm.nih.gov/pubmed/27257011 http://dx.doi.org/10.4062/biomolther.2016.008

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