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A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

BACKGROUND & AIMS: The lack of a preclinical model of progressive non-alcoholic steatohepatitis (NASH) that recapitulates human disease is a barrier to therapeutic development. METHODS: A stable isogenic cross between C57BL/6J (B6) and 129S1/SvImJ (S129) mice were fed a high fat diet with ad lib...

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Detalles Bibliográficos
Autores principales:	Asgharpour, Amon, Cazanave, Sophie C., Pacana, Tommy, Seneshaw, Mulugeta, Vincent, Robert, Banini, Bubu A., Kumar, Divya Prasanna, Daita, Kalyani, Min, Hae-Ki, Mirshahi, Faridoddin, Bedossa, Pierre, Sun, Xiaochen, Hoshida, Yujin, Koduru, Srinivas V., Contaifer, Daniel, Warncke, Urszula Osinska, Wijesinghe, Dayanjan S., Sanyal, Arun J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012902/ https://www.ncbi.nlm.nih.gov/pubmed/27261415 http://dx.doi.org/10.1016/j.jhep.2016.05.005

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