Cargando…
Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein‐specific antibodies
Alzheimer's disease (AD) is histopathologically characterized by neurodegeneration, the formation of intracellular neurofibrillary tangles and extracellular Aβ deposits that derive from proteolytic processing of the amyloid precursor protein (APP). As rodents do not normally develop Aβ patholog...
Autores principales: | Höfling, Corinna, Morawski, Markus, Zeitschel, Ulrike, Zanier, Elisa R., Moschke, Katrin, Serdaroglu, Alperen, Canneva, Fabio, von Hörsten, Stephan, De Simoni, Maria‐Grazia, Forloni, Gianluigi, Jäger, Carsten, Kremmer, Elisabeth, Roßner, Steffen, Lichtenthaler, Stefan F., Kuhn, Peer‐Hendrik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013031/ https://www.ncbi.nlm.nih.gov/pubmed/27470171 http://dx.doi.org/10.1111/acel.12508 |
Ejemplares similares
-
Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain
por: Heiland, Tina, et al.
Publicado: (2018) -
Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer’s Disease
por: Höfling, Corinna, et al.
Publicado: (2019) -
Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer’s disease
por: Hartlage-Rübsamen, Maike, et al.
Publicado: (2019) -
Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation
por: Hartlage-Rübsamen, Maike, et al.
Publicado: (2018) -
Peptide backbone modifications of amyloid β (1–40) impact fibrillation behavior and neuronal toxicity
por: Schwarze, Benedikt, et al.
Publicado: (2021)