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Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response
Given the high costs of conducting a drug-response trial, researchers are now aiming to use retrospective analyses to conduct genome-wide association studies (GWAS) to identify underlying genetic contributions to drug-response variation. To prevent confounding results from a GWAS to investigate drug...
Autores principales: | Graham, Hillary T., Rotroff, Daniel M., Marvel, Skylar W., Buse, John B., Havener, Tammy M., Wilson, Alyson G., Wagner, Michael J., Motsinger-Reif, Alison A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013254/ https://www.ncbi.nlm.nih.gov/pubmed/27775101 http://dx.doi.org/10.3389/fgene.2016.00138 |
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