miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer

Dysregulation of PI3K and MAPK pathways promotes uncontrolled cell proliferation, apoptotic inhibition and metastasis. Individual targeting of these pathways using kinase inhibitors has largely been insufficient due to the existence of cross-talks between these parallel cascades. MicroRNAs are small...

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Detalles Bibliográficos
Autores principales: Mutlu, Merve, Saatci, Özge, Ansari, Suhail A., Yurdusev, Emre, Shehwana, Huma, Konu, Özlen, Raza, Umar, Şahin, Özgür
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013276/
https://www.ncbi.nlm.nih.gov/pubmed/27600857
http://dx.doi.org/10.1038/srep32541

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