aroA-Deficient Salmonella enterica Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant

Recombinant attenuated Salmonella enterica serovar Typhimurium strains are believed to act as powerful live vaccine carriers that are able to elicit protection against various pathogens. Auxotrophic mutations, such as a deletion of aroA, are commonly introduced into such bacteria for attenuation wit...

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Detalles Bibliográficos
Autores principales: Felgner, Sebastian, Frahm, Michael, Kocijancic, Dino, Rohde, Manfred, Eckweiler, Denitsa, Bielecka, Agata, Bueno, Emilio, Cava, Felipe, Abraham, Wolf-Rainer, Curtiss, Roy, Häussler, Susanne, Erhardt, Marc, Weiss, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013297/
https://www.ncbi.nlm.nih.gov/pubmed/27601574
http://dx.doi.org/10.1128/mBio.01220-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013297/
https://www.ncbi.nlm.nih.gov/pubmed/27601574
http://dx.doi.org/10.1128/mBio.01220-16

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