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aroA-Deficient Salmonella enterica Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant
Recombinant attenuated Salmonella enterica serovar Typhimurium strains are believed to act as powerful live vaccine carriers that are able to elicit protection against various pathogens. Auxotrophic mutations, such as a deletion of aroA, are commonly introduced into such bacteria for attenuation wit...
Autores principales: | Felgner, Sebastian, Frahm, Michael, Kocijancic, Dino, Rohde, Manfred, Eckweiler, Denitsa, Bielecka, Agata, Bueno, Emilio, Cava, Felipe, Abraham, Wolf-Rainer, Curtiss, Roy, Häussler, Susanne, Erhardt, Marc, Weiss, Siegfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013297/ https://www.ncbi.nlm.nih.gov/pubmed/27601574 http://dx.doi.org/10.1128/mBio.01220-16 |
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