TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis

There is now compelling evidence that TNFR2 is constitutively expressed on CD4(+) Foxp3(+) regulatory T cells (Tregs) and TNF-TNFR2 interaction is critical for the activation, expansion and functional stability of Tregs. However, we showed that the expression of TNFR2 was also up-regulated on CD4(+)...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Nie, Yingjie, Xiao, Haitao, Bian, Zhaoxiang, Scarzello, Anthony J., Song, Na-Young, Trivett, Anna L., Yang, De, Oppenheim, Joost J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013387/
https://www.ncbi.nlm.nih.gov/pubmed/27601345
http://dx.doi.org/10.1038/srep32834

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