Cargando…

Body mass index and psychiatric disorders: a Mendelian randomization study

Obesity is a highly prevalent risk factor for cardiometabolic diseases. Observational studies suggest that obesity is associated with psychiatric traits, but causal inference from such studies has several limitations. We used two-sample Mendelian randomization methods (inverse variance weighting, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hartwig, Fernando Pires, Bowden, Jack, Loret de Mola, Christian, Tovo-Rodrigues, Luciana, Davey Smith, George, Horta, Bernardo Lessa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013405/ https://www.ncbi.nlm.nih.gov/pubmed/27601421 http://dx.doi.org/10.1038/srep32730

Ejemplares similares

Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
por: Hartwig, Fernando Pires, et al.
Publicado: (2016)

Inflammatory Biomarkers and Risk of Schizophrenia: A 2-Sample Mendelian Randomization Study
por: Hartwig, Fernando Pires, et al.
Publicado: (2017)

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption
por: Hartwig, Fernando Pires, et al.
Publicado: (2017)

Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions
por: Spiller, Wes, et al.
Publicado: (2022)

Quality of life in adults from a rural area in Southern Brazil: a population-based study
por: Bortolotto, Caroline Cardozo, et al.
Publicado: (2018)

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: protocol for a collaborative meta-analysis
por: Hartwig, Fernando Pires, et al.
Publicado: (2016)

Genomic ancestry and the social pathways leading to major depression in adulthood: the mediating effect of socioeconomic position and discrimination
por: Loret de Mola, Christian, et al.
Publicado: (2016)

Bias in Mendelian randomization due to assortative mating
por: Hartwig, Fernando Pires, et al.
Publicado: (2018)

Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study
por: Karageorgiou, Vasilios, et al.
Publicado: (2023)

Association between breastfeeding and intelligence, educational attainment, and income at 30 years of age: a prospective birth cohort study from Brazil
por: Victora, Cesar G, et al.
Publicado: (2015)

General and abdominal obesity in adults living in a rural area in Southern Brazil
por: Martins-Silva, Thais, et al.
Publicado: (2018)

Performance of Body Fat Percentage, Fat Mass Index and Body Mass Index for Detecting Cardiometabolic Outcomes in Brazilian Adults
por: de Oliveira, Bianca Rodrigues, et al.
Publicado: (2023)

Associations of Linear Growth and Relative Weight Gain in Early Life with Human Capital at 30 Years of Age
por: Horta, Bernardo Lessa, et al.
Publicado: (2017)

Breastfeeding and mental health in adulthood: A birth cohort study in Brazil
por: Loret de Mola, Christian, et al.
Publicado: (2016)

Evaluating the potential role of pleiotropy in Mendelian randomization studies
por: Hemani, Gibran, et al.
Publicado: (2018)

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique
por: Hartwig, Fernando Pires, et al.
Publicado: (2016)

The Effect of Fetal and Childhood Growth over Depression in Early Adulthood in a Southern Brazilian Birth Cohort
por: Loret de Mola, Christian, et al.
Publicado: (2015)

The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study
por: Taylor, Amy E, et al.
Publicado: (2019)

Associations between body mass index, body composition and bone density in young adults: findings from a southern Brazilian cohort
por: Bierhals, Isabel Oliveira, et al.
Publicado: (2019)

Education and coronary heart disease: mendelian randomisation study
por: Tillmann, Taavi, et al.
Publicado: (2017)

Is there a causal role for homocysteine concentration in blood pressure? A Mendelian randomization study(1)(2)
por: Borges, Maria C, et al.
Publicado: (2016)

Bias in two-sample Mendelian randomization when using heritable covariable-adjusted summary associations
por: Hartwig, Fernando Pires, et al.
Publicado: (2021)

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
por: Bowden, Jack, et al.
Publicado: (2015)

C-reactive protein levels and body mass index: Elucidating direction of causation through reciprocal Mendelian randomization
por: Timpson, Nicholas J., et al.
Publicado: (2010)

Body Mass Index and Self-Perception of Overweight and Obesity in Rural, Urban and Rural-to-Urban Migrants: PERU MIGRANT Study
por: Loret de Mola, Christian, et al.
Publicado: (2012)

Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization
por: Millard, Louise A. C., et al.
Publicado: (2019)

Detecting and correcting for bias in Mendelian randomization analyses using Gene-by-Environment interactions
por: Spiller, Wes, et al.
Publicado: (2019)

Breastfeeding effects on DNA methylation in the offspring: A systematic literature review
por: Hartwig, Fernando Pires, et al.
Publicado: (2017)

Correction: Breastfeeding effects on DNA methylation in the offspring: A systematic literature review
por: Hartwig, Fernando Pires, et al.
Publicado: (2017)

Invited Commentary: Detecting Individual and Global Horizontal Pleiotropy in Mendelian Randomization—A Job for the Humble Heterogeneity Statistic?
por: Bowden, Jack, et al.
Publicado: (2018)

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings
por: Sanderson, Eleanor, et al.
Publicado: (2019)

Cohort Profile Update: The 1982 Pelotas (Brazil) Birth Cohort Study
por: Horta, Bernardo Lessa, et al.
Publicado: (2015)

Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour
por: Sanderson, Eleanor, et al.
Publicado: (2019)

MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization
por: Millard, Louise A. C., et al.
Publicado: (2015)

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study
por: Noyce, Alastair J., et al.
Publicado: (2017)

The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach
por: Nordestgaard, Børge G., et al.
Publicado: (2012)

Corrigendum to: An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings
por: Sanderson, Eleanor, et al.
Publicado: (2020)

Body mass index and breast cancer survival: a Mendelian randomization analysis
por: Guo, Qi, et al.
Publicado: (2017)

Disentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation
por: Leyden, Genevieve M., et al.
Publicado: (2022)

Mendelian randomisation with coarsened exposures
por: Tudball, Matthew J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_abaq77db469gq15qah2f6mf6d7