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Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol

INTRODUCTION: Functional gastrointestinal disorders (FGIDs) and FGID-related signs and symptoms have a fundamental impact on the psychosocial, physical and mental well-being of infants and their parents alike. Recent reviews and studies have indicated that FGIDs and related signs and symptoms may al...

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Autores principales: Glanville, Julie, Ludwig, Thomas, Lifschitz, Carlos, Mahon, James, Miqdady, Mohamad, Saps, Miguel, Hock Quak, Seng, Lenoir-Wijnkoop, Irene, Edwards, Mary, Wood, Hannah, Szajewska, Hania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013437/
https://www.ncbi.nlm.nih.gov/pubmed/27558903
http://dx.doi.org/10.1136/bmjopen-2016-011475
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author Glanville, Julie
Ludwig, Thomas
Lifschitz, Carlos
Mahon, James
Miqdady, Mohamad
Saps, Miguel
Hock Quak, Seng
Lenoir-Wijnkoop, Irene
Edwards, Mary
Wood, Hannah
Szajewska, Hania
author_facet Glanville, Julie
Ludwig, Thomas
Lifschitz, Carlos
Mahon, James
Miqdady, Mohamad
Saps, Miguel
Hock Quak, Seng
Lenoir-Wijnkoop, Irene
Edwards, Mary
Wood, Hannah
Szajewska, Hania
author_sort Glanville, Julie
collection PubMed
description INTRODUCTION: Functional gastrointestinal disorders (FGIDs) and FGID-related signs and symptoms have a fundamental impact on the psychosocial, physical and mental well-being of infants and their parents alike. Recent reviews and studies have indicated that FGIDs and related signs and symptoms may also have a substantial impact on the budgets of third-party payers and/or parents. The objective of this systematic review is to investigate these costs. METHODS AND ANALYSIS: The population of interest is healthy term infants (under 12 months of age) with colic, regurgitation and/or functional constipation. Outcomes of interest will include the frequency and volume of reported treatments, the cost to third-party payers and/or parents for prescribed or over the counter treatments, visits to health professionals and changes in infant formula purchases, and the loss of income through time taken off work and out of pocket costs. Relevant studies will be identified by searching databases from 2005 onwards (including MEDLINE, EMBASE, PsycINFO, NEXIS, DARE, Health Technology Assessment database, National Health Service Economic Evaluation Database and others), conferences from the previous 3 years and scanning reference lists of eligible studies. Study selection, data extraction and quality assessment will be conducted by two independent reviewers and disagreements resolved in discussion with a third reviewer. Quality assessment will involve study design-specific checklists. Relevant studies will be summarised narratively and presented in tables. An overview of treatments and costs will be provided, with any geographical or other differences highlighted. An assessment of how the totals for cost differ across countries and elements that contribute to the differences will be generated. ETHICS AND DISSEMINATION: This is a systematic review of published studies that will be submitted for publication to a peer-reviewed journal. Ethical committee approval is not required. TRIAL REGISTRATION NUMBER: CRD42016033119.
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spelling pubmed-50134372016-09-12 Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol Glanville, Julie Ludwig, Thomas Lifschitz, Carlos Mahon, James Miqdady, Mohamad Saps, Miguel Hock Quak, Seng Lenoir-Wijnkoop, Irene Edwards, Mary Wood, Hannah Szajewska, Hania BMJ Open Paediatrics INTRODUCTION: Functional gastrointestinal disorders (FGIDs) and FGID-related signs and symptoms have a fundamental impact on the psychosocial, physical and mental well-being of infants and their parents alike. Recent reviews and studies have indicated that FGIDs and related signs and symptoms may also have a substantial impact on the budgets of third-party payers and/or parents. The objective of this systematic review is to investigate these costs. METHODS AND ANALYSIS: The population of interest is healthy term infants (under 12 months of age) with colic, regurgitation and/or functional constipation. Outcomes of interest will include the frequency and volume of reported treatments, the cost to third-party payers and/or parents for prescribed or over the counter treatments, visits to health professionals and changes in infant formula purchases, and the loss of income through time taken off work and out of pocket costs. Relevant studies will be identified by searching databases from 2005 onwards (including MEDLINE, EMBASE, PsycINFO, NEXIS, DARE, Health Technology Assessment database, National Health Service Economic Evaluation Database and others), conferences from the previous 3 years and scanning reference lists of eligible studies. Study selection, data extraction and quality assessment will be conducted by two independent reviewers and disagreements resolved in discussion with a third reviewer. Quality assessment will involve study design-specific checklists. Relevant studies will be summarised narratively and presented in tables. An overview of treatments and costs will be provided, with any geographical or other differences highlighted. An assessment of how the totals for cost differ across countries and elements that contribute to the differences will be generated. ETHICS AND DISSEMINATION: This is a systematic review of published studies that will be submitted for publication to a peer-reviewed journal. Ethical committee approval is not required. TRIAL REGISTRATION NUMBER: CRD42016033119. BMJ Publishing Group 2016-08-24 /pmc/articles/PMC5013437/ /pubmed/27558903 http://dx.doi.org/10.1136/bmjopen-2016-011475 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Paediatrics
Glanville, Julie
Ludwig, Thomas
Lifschitz, Carlos
Mahon, James
Miqdady, Mohamad
Saps, Miguel
Hock Quak, Seng
Lenoir-Wijnkoop, Irene
Edwards, Mary
Wood, Hannah
Szajewska, Hania
Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
title Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
title_full Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
title_fullStr Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
title_full_unstemmed Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
title_short Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
title_sort costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol
topic Paediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013437/
https://www.ncbi.nlm.nih.gov/pubmed/27558903
http://dx.doi.org/10.1136/bmjopen-2016-011475
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