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G-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53

p53 preserves genomic integrity by restricting anomaly at the gene level. Till date, limited information is available for cytosol to nuclear shuttling of p53; except microtubule-based trafficking route, which utilizes minus-end directed motor dynein. The present study suggests that monomeric actin (...

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Detalles Bibliográficos
Autores principales: Saha, Taniya, Guha, Deblina, Manna, Argha, Panda, Abir Kumar, Bhat, Jyotsna, Chatterjee, Subhrangsu, Sa, Gaurisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013524/
https://www.ncbi.nlm.nih.gov/pubmed/27601274
http://dx.doi.org/10.1038/srep32626

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