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Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes
[Image: see text] Indolizidine and quinolizidine derivatives are readily assembled from proline or pipecolic acid and γ-nitroaldehydes by means of a decarboxylative annulation process. These reactions are promoted by simple acetic acid and involve azomethine ylides as reactive intermediates. The met...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013532/ https://www.ncbi.nlm.nih.gov/pubmed/27509449 http://dx.doi.org/10.1021/acs.orglett.6b02020 |
| _version_ | 1782452185458540544 |
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| author | Kang, YoungKu Seidel, Daniel |
| author_facet | Kang, YoungKu Seidel, Daniel |
| author_sort | Kang, YoungKu |
| collection | PubMed |
| description | [Image: see text] Indolizidine and quinolizidine derivatives are readily assembled from proline or pipecolic acid and γ-nitroaldehydes by means of a decarboxylative annulation process. These reactions are promoted by simple acetic acid and involve azomethine ylides as reactive intermediates. The method was applied to the synthesis of an epiquinamide analog. |
| format | Online Article Text |
| id | pubmed-5013532 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | American Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-50135322016-09-08 Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes Kang, YoungKu Seidel, Daniel Org Lett [Image: see text] Indolizidine and quinolizidine derivatives are readily assembled from proline or pipecolic acid and γ-nitroaldehydes by means of a decarboxylative annulation process. These reactions are promoted by simple acetic acid and involve azomethine ylides as reactive intermediates. The method was applied to the synthesis of an epiquinamide analog. American Chemical Society 2016-08-10 2016-09-02 /pmc/articles/PMC5013532/ /pubmed/27509449 http://dx.doi.org/10.1021/acs.orglett.6b02020 Text en Copyright © 2016 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
| spellingShingle | Kang, YoungKu Seidel, Daniel Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes |
| title | Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes |
| title_full | Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes |
| title_fullStr | Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes |
| title_full_unstemmed | Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes |
| title_short | Decarboxylative Annulation of α-Amino Acids with γ-Nitroaldehydes |
| title_sort | decarboxylative annulation of α-amino acids with γ-nitroaldehydes |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013532/ https://www.ncbi.nlm.nih.gov/pubmed/27509449 http://dx.doi.org/10.1021/acs.orglett.6b02020 |
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