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Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia

OBJECTIVE: To assess the prevalence of diabetes mellitus (DM) and associated factors among HIV-infected adults in northwest Ethiopia. DESIGN: Hospital-based cross-sectional study. SETTING: HIV clinic of the University of Gondar Hospital, Ethiopia. PARTICIPANTS: All HIV-infected adults who visited th...

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Autores principales: Abebe, Solomon Mekonnen, Getachew, Assefa, Fasika, Solomon, Bayisa, Mulugeta, Girma Demisse, Abayneh, Mesfin, Nebiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013550/
https://www.ncbi.nlm.nih.gov/pubmed/27540099
http://dx.doi.org/10.1136/bmjopen-2016-011175
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author Abebe, Solomon Mekonnen
Getachew, Assefa
Fasika, Solomon
Bayisa, Mulugeta
Girma Demisse, Abayneh
Mesfin, Nebiyu
author_facet Abebe, Solomon Mekonnen
Getachew, Assefa
Fasika, Solomon
Bayisa, Mulugeta
Girma Demisse, Abayneh
Mesfin, Nebiyu
author_sort Abebe, Solomon Mekonnen
collection PubMed
description OBJECTIVE: To assess the prevalence of diabetes mellitus (DM) and associated factors among HIV-infected adults in northwest Ethiopia. DESIGN: Hospital-based cross-sectional study. SETTING: HIV clinic of the University of Gondar Hospital, Ethiopia. PARTICIPANTS: All HIV-infected adults who visited the HIV clinic from December 2013 to the end of February 2014 were the source population. MEASURES: A structured and pretested questionnaire incorporating the WHO STEPwise approach was used. A multivariate logistic regression analysis was applied to assess factors associated with DM. RESULTS: The overall prevalence of type 2 DM was 8% (95% CI 5.5% to 10.5%). The prevalence of DM was higher (13.2%; 95% CI 8.0% to 18.3%) among subjects receiving pre-antiretroviral treatment (pre-ART) than among those taking ART (5.1%; 95% CI 2.6% to 7.6%). Thirteen (35.1%) of the DM cases were newly identified during the study. Obesity (adjusted OR (AOR) 6.55; 1.20 to 35.8), hypertension (AOR 3.45; 1.50 to 7.90), being in the pre-ART group (AOR 4.47; 1.80 to 11.08), hypertriglyceridaemia (AOR 2.24; 1.02 to 49.5) and tertiary-level education (AOR 11.8; 2.28 to 61.4) were associated with DM. CONCLUSIONS: Overall DM prevalence was high, particularly among subjects in the pre-ART group. More educated, hypertensive and obese HIV-infected adults were more likely to have DM as a comorbidity. Health policy and the clinical management of HIV-infected individuals should take into account the rising DM.
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spelling pubmed-50135502016-09-12 Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia Abebe, Solomon Mekonnen Getachew, Assefa Fasika, Solomon Bayisa, Mulugeta Girma Demisse, Abayneh Mesfin, Nebiyu BMJ Open Diabetes and Endocrinology OBJECTIVE: To assess the prevalence of diabetes mellitus (DM) and associated factors among HIV-infected adults in northwest Ethiopia. DESIGN: Hospital-based cross-sectional study. SETTING: HIV clinic of the University of Gondar Hospital, Ethiopia. PARTICIPANTS: All HIV-infected adults who visited the HIV clinic from December 2013 to the end of February 2014 were the source population. MEASURES: A structured and pretested questionnaire incorporating the WHO STEPwise approach was used. A multivariate logistic regression analysis was applied to assess factors associated with DM. RESULTS: The overall prevalence of type 2 DM was 8% (95% CI 5.5% to 10.5%). The prevalence of DM was higher (13.2%; 95% CI 8.0% to 18.3%) among subjects receiving pre-antiretroviral treatment (pre-ART) than among those taking ART (5.1%; 95% CI 2.6% to 7.6%). Thirteen (35.1%) of the DM cases were newly identified during the study. Obesity (adjusted OR (AOR) 6.55; 1.20 to 35.8), hypertension (AOR 3.45; 1.50 to 7.90), being in the pre-ART group (AOR 4.47; 1.80 to 11.08), hypertriglyceridaemia (AOR 2.24; 1.02 to 49.5) and tertiary-level education (AOR 11.8; 2.28 to 61.4) were associated with DM. CONCLUSIONS: Overall DM prevalence was high, particularly among subjects in the pre-ART group. More educated, hypertensive and obese HIV-infected adults were more likely to have DM as a comorbidity. Health policy and the clinical management of HIV-infected individuals should take into account the rising DM. BMJ Publishing Group 2016-08-18 /pmc/articles/PMC5013550/ /pubmed/27540099 http://dx.doi.org/10.1136/bmjopen-2016-011175 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Diabetes and Endocrinology
Abebe, Solomon Mekonnen
Getachew, Assefa
Fasika, Solomon
Bayisa, Mulugeta
Girma Demisse, Abayneh
Mesfin, Nebiyu
Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia
title Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia
title_full Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia
title_fullStr Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia
title_full_unstemmed Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia
title_short Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia
title_sort diabetes mellitus among hiv-infected individuals in follow-up care at university of gondar hospital, northwest ethiopia
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013550/
https://www.ncbi.nlm.nih.gov/pubmed/27540099
http://dx.doi.org/10.1136/bmjopen-2016-011175
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