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Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest

BACKGROUND: Data of the TraumaRegister DGU® were analyzed to derive survival rates, neurological outcome and prognostic factors of patients who had suffered traumatic cardiac arrest in the early treatment phase. METHODS: The database of the TraumaRegister DGU® from 2002 to 2013 was analyzed. The mai...

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Autores principales: Zwingmann, J., Lefering, R., Feucht, M., Südkamp, N. P., Strohm, P. C., Hammer, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013586/
https://www.ncbi.nlm.nih.gov/pubmed/27600396
http://dx.doi.org/10.1186/s13054-016-1463-6
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author Zwingmann, J.
Lefering, R.
Feucht, M.
Südkamp, N. P.
Strohm, P. C.
Hammer, T.
author_facet Zwingmann, J.
Lefering, R.
Feucht, M.
Südkamp, N. P.
Strohm, P. C.
Hammer, T.
author_sort Zwingmann, J.
collection PubMed
description BACKGROUND: Data of the TraumaRegister DGU® were analyzed to derive survival rates, neurological outcome and prognostic factors of patients who had suffered traumatic cardiac arrest in the early treatment phase. METHODS: The database of the TraumaRegister DGU® from 2002 to 2013 was analyzed. The main focus of this survey was on different time points of performed resuscitation. Descriptive and multivariate analyses (logistic regression) were performed with the neurological outcome (Glasgow Outcome Scale) and survival rate as the target variable. Patients were classified according to CPR in the prehospital phase and/or in the emergency room (ER). Patients without CA served as a control group. The database does not include patients who required prehospital CPR but did not achieve ROSC. RESULTS: A total of 3052 patients from a total of 38,499 cases had cardiac arrest during the early post-trauma phase and required CPR in the prehospital phase and/or in the ER. After only prehospital resuscitation (n = 944) survival rate was 31.7 %, and 14.7 % had a good/moderate outcome. If CPR was required in the ER only (n = 1197), survival rate was 25.6 %, with a good/moderate outcome in 19.2 % of cases. A total of 4.8 % in the group with preclinical and ER resuscitation survived, and just 2.7 % had a good or moderate outcome. Multivariate logistic regression analysis revealed the following prognostic factors for survival after traumatic cardiac arrest: prehospital CPR, shock, coagulopathy, thorax drainage, preclinical catecholamines, unconsciousness, and injury severity (Injury Severity Score). CONCLUSIONS: With the knowledge that prehospital resuscitated patients who not reached the hospital could not be included, CPR after severe trauma seems to yield a better outcome than most studies have reported, and appears to be more justified than the current guidelines would imply. Preclinical resuscitation is associated with a higher survival rate and better neurological outcome compared with resuscitation in the ER. If resuscitation in the ER is necessary after a preclinical performed resuscitation the survival rate is marginal, even though 56 % of these patients had a good and moderate outcome. The data we present may support algorithms for resuscitation in the future.
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spelling pubmed-50135862016-09-08 Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest Zwingmann, J. Lefering, R. Feucht, M. Südkamp, N. P. Strohm, P. C. Hammer, T. Crit Care Research BACKGROUND: Data of the TraumaRegister DGU® were analyzed to derive survival rates, neurological outcome and prognostic factors of patients who had suffered traumatic cardiac arrest in the early treatment phase. METHODS: The database of the TraumaRegister DGU® from 2002 to 2013 was analyzed. The main focus of this survey was on different time points of performed resuscitation. Descriptive and multivariate analyses (logistic regression) were performed with the neurological outcome (Glasgow Outcome Scale) and survival rate as the target variable. Patients were classified according to CPR in the prehospital phase and/or in the emergency room (ER). Patients without CA served as a control group. The database does not include patients who required prehospital CPR but did not achieve ROSC. RESULTS: A total of 3052 patients from a total of 38,499 cases had cardiac arrest during the early post-trauma phase and required CPR in the prehospital phase and/or in the ER. After only prehospital resuscitation (n = 944) survival rate was 31.7 %, and 14.7 % had a good/moderate outcome. If CPR was required in the ER only (n = 1197), survival rate was 25.6 %, with a good/moderate outcome in 19.2 % of cases. A total of 4.8 % in the group with preclinical and ER resuscitation survived, and just 2.7 % had a good or moderate outcome. Multivariate logistic regression analysis revealed the following prognostic factors for survival after traumatic cardiac arrest: prehospital CPR, shock, coagulopathy, thorax drainage, preclinical catecholamines, unconsciousness, and injury severity (Injury Severity Score). CONCLUSIONS: With the knowledge that prehospital resuscitated patients who not reached the hospital could not be included, CPR after severe trauma seems to yield a better outcome than most studies have reported, and appears to be more justified than the current guidelines would imply. Preclinical resuscitation is associated with a higher survival rate and better neurological outcome compared with resuscitation in the ER. If resuscitation in the ER is necessary after a preclinical performed resuscitation the survival rate is marginal, even though 56 % of these patients had a good and moderate outcome. The data we present may support algorithms for resuscitation in the future. BioMed Central 2016-09-06 /pmc/articles/PMC5013586/ /pubmed/27600396 http://dx.doi.org/10.1186/s13054-016-1463-6 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Zwingmann, J.
Lefering, R.
Feucht, M.
Südkamp, N. P.
Strohm, P. C.
Hammer, T.
Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
title Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
title_full Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
title_fullStr Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
title_full_unstemmed Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
title_short Outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
title_sort outcome and predictors for successful resuscitation in the emergency room of adult patients in traumatic cardiorespiratory arrest
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013586/
https://www.ncbi.nlm.nih.gov/pubmed/27600396
http://dx.doi.org/10.1186/s13054-016-1463-6
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