Regulation of monocyte cell fate by blood vessels mediated by Notch signalling

A population of monocytes, known as Ly6C(lo) monocytes, patrol blood vessels by crawling along the vascular endothelium. Here we show that endothelial cells control their origin through Notch signalling. Using combinations of conditional genetic deletion strategies and cell-fate tracking experiments...

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Detalles Bibliográficos
Autores principales: Gamrekelashvili, Jaba, Giagnorio, Roberto, Jussofie, Jasmin, Soehnlein, Oliver, Duchene, Johan, Briseño, Carlos G., Ramasamy, Saravana K., Krishnasamy, Kashyap, Limbourg, Anne, Häger, Christine, Kapanadze, Tamar, Ishifune, Chieko, Hinkel, Rabea, Radtke, Freddy, Strobl, Lothar J., Zimber-Strobl, Ursula, Napp, L. Christian, Bauersachs, Johann, Haller, Hermann, Yasutomo, Koji, Kupatt, Christian, Murphy, Kenneth M., Adams, Ralf H., Weber, Christian, Limbourg, Florian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013671/
https://www.ncbi.nlm.nih.gov/pubmed/27576369
http://dx.doi.org/10.1038/ncomms12597

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