Bis-biguanide dihydrochloride inhibits intracellular replication of M. tuberculosis and controls infection in mice

While there is an urgent need to develop new and effective drugs for treatment of tuberculosis (TB) and multi-drug resistant TB (MDR-TB), repurposing FDA (U.S. Food and Drug Administration) -approved drugs for development of anti-TB agents may decrease time and effort from bench to bedside. Here, we...

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Detalles Bibliográficos
Autores principales: Shen, Hongbo, Wang, Feifei, Zeng, Gucheng, Shen, Ling, Cheng, Han, Huang, Dan, Wang, Richard, Rong, Lijun, Chen, Zheng W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013693/
https://www.ncbi.nlm.nih.gov/pubmed/27601302
http://dx.doi.org/10.1038/srep32725

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