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Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index

INTRODUCTION: Peritonitis is one of the most common problems in general surgery practice with high mortality rate. One of the reasons for high mortality is that peritonitis affects the general condition and leads to complications causing multiple organ failure, renal failure, sepsis, and postoperati...

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Autores principales: Sharma, Sanjeev, Singh, Sumitoj, Makkar, Nikhil, Kumar, Ashok, Sandhu, Mandeep Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013738/
https://www.ncbi.nlm.nih.gov/pubmed/27843277
http://dx.doi.org/10.4103/1117-6806.189009
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author Sharma, Sanjeev
Singh, Sumitoj
Makkar, Nikhil
Kumar, Ashok
Sandhu, Mandeep Singh
author_facet Sharma, Sanjeev
Singh, Sumitoj
Makkar, Nikhil
Kumar, Ashok
Sandhu, Mandeep Singh
author_sort Sharma, Sanjeev
collection PubMed
description INTRODUCTION: Peritonitis is one of the most common problems in general surgery practice with high mortality rate. One of the reasons for high mortality is that peritonitis affects the general condition and leads to complications causing multiple organ failure, renal failure, sepsis, and postoperative ventilatory support. Early prognostic evaluation of patients with peritonitis is desirable to select high-risk patients for intensive management and also to provide a reliable objective classification of severity and operative risk. PATIENTS AND METHODS: Fifty cases with diagnosis of peritonitis coming to Government Medical College, Amritsar, were studied. Stratification of these patients was done according to Mannheim peritonitis index (MPI), and their outcome was examined. RESULTS: Mortality steadily increases with increase in MPI score. For patients with a score <21, the mortality rate was 0%; for score 21–27, it was 27.28%; and for score >27, it was 100% (P < 0.001). For patients with a score <21, the morbidity rate was 13.33%; for score 21-27, it was 65.71%; and for score >27, it was 100% (P < 0.001). Duration of pain >24 h, organ failure on admission, female sex, and feculent exudate were found to be independently significant factors in predicting the mortality among the study population. For a score of 27, the sensitivity was 66.67%, specificity was 100%, and positive predictive value for mortality is 100% at an accuracy of 94%. CONCLUSION: This study proves that MPI scoring system is a simple and effective tool for assessing the morbidity and mortality in patients with peritonitis.
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spelling pubmed-50137382016-11-14 Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index Sharma, Sanjeev Singh, Sumitoj Makkar, Nikhil Kumar, Ashok Sandhu, Mandeep Singh Niger J Surg Original Article INTRODUCTION: Peritonitis is one of the most common problems in general surgery practice with high mortality rate. One of the reasons for high mortality is that peritonitis affects the general condition and leads to complications causing multiple organ failure, renal failure, sepsis, and postoperative ventilatory support. Early prognostic evaluation of patients with peritonitis is desirable to select high-risk patients for intensive management and also to provide a reliable objective classification of severity and operative risk. PATIENTS AND METHODS: Fifty cases with diagnosis of peritonitis coming to Government Medical College, Amritsar, were studied. Stratification of these patients was done according to Mannheim peritonitis index (MPI), and their outcome was examined. RESULTS: Mortality steadily increases with increase in MPI score. For patients with a score <21, the mortality rate was 0%; for score 21–27, it was 27.28%; and for score >27, it was 100% (P < 0.001). For patients with a score <21, the morbidity rate was 13.33%; for score 21-27, it was 65.71%; and for score >27, it was 100% (P < 0.001). Duration of pain >24 h, organ failure on admission, female sex, and feculent exudate were found to be independently significant factors in predicting the mortality among the study population. For a score of 27, the sensitivity was 66.67%, specificity was 100%, and positive predictive value for mortality is 100% at an accuracy of 94%. CONCLUSION: This study proves that MPI scoring system is a simple and effective tool for assessing the morbidity and mortality in patients with peritonitis. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5013738/ /pubmed/27843277 http://dx.doi.org/10.4103/1117-6806.189009 Text en Copyright: © Nigerian Journal of Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sharma, Sanjeev
Singh, Sumitoj
Makkar, Nikhil
Kumar, Ashok
Sandhu, Mandeep Singh
Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index
title Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index
title_full Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index
title_fullStr Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index
title_full_unstemmed Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index
title_short Assessment of Severity of Peritonitis Using Mannheim Peritonitis Index
title_sort assessment of severity of peritonitis using mannheim peritonitis index
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013738/
https://www.ncbi.nlm.nih.gov/pubmed/27843277
http://dx.doi.org/10.4103/1117-6806.189009
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