ProbOnto: ontology and knowledge base of probability distributions

Motivation: Probability distributions play a central role in mathematical and statistical modelling. The encoding, annotation and exchange of such models could be greatly simplified by a resource providing a common reference for the definition of probability distributions. Although some resources exist, no suitably detailed and complex ontology exists nor any database allowing programmatic access. Results: ProbOnto, is an ontology-based knowledge base of probability distributions, featuring more than 80 uni- and multivariate distributions with their defining functions, characteristics, relationships and re-parameterization formulas. It can be used for model annotation and facilitates the encoding of distribution-based models, related functions and quantities. Availability and Implementation: http://probonto.org Contact: mjswat@ebi.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online.