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Tools4miRs – one place to gather all the tools for miRNA analysis

Summary: MiRNAs are short, non-coding molecules that negatively regulate gene expression and thereby play several important roles in living organisms. Dozens of computational methods for miRNA-related research have been developed, which greatly differ in various aspects. The substantial availability...

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Detalles Bibliográficos
Autores principales: Lukasik, Anna, Wójcikowski, Maciej, Zielenkiewicz, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013900/
https://www.ncbi.nlm.nih.gov/pubmed/27153626
http://dx.doi.org/10.1093/bioinformatics/btw189
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author Lukasik, Anna
Wójcikowski, Maciej
Zielenkiewicz, Piotr
author_facet Lukasik, Anna
Wójcikowski, Maciej
Zielenkiewicz, Piotr
author_sort Lukasik, Anna
collection PubMed
description Summary: MiRNAs are short, non-coding molecules that negatively regulate gene expression and thereby play several important roles in living organisms. Dozens of computational methods for miRNA-related research have been developed, which greatly differ in various aspects. The substantial availability of difficult-to-compare approaches makes it challenging for the user to select a proper tool and prompts the need for a solution that will collect and categorize all the methods. Here, we present tools4miRs, the first platform that gathers currently more than 160 methods for broadly defined miRNA analysis. The collected tools are classified into several general and more detailed categories in which the users can additionally filter the available methods according to their specific research needs, capabilities and preferences. Tools4miRs is also a web-based target prediction meta-server that incorporates user-designated target prediction methods into the analysis of user-provided data. Availability and Implementation: Tools4miRs is implemented in Python using Django and is freely available at tools4mirs.org. Contact: piotr@ibb.waw.pl Supplementary information: Supplementary data are available at Bioinformatics online.
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spelling pubmed-50139002016-09-12 Tools4miRs – one place to gather all the tools for miRNA analysis Lukasik, Anna Wójcikowski, Maciej Zielenkiewicz, Piotr Bioinformatics Applications Notes Summary: MiRNAs are short, non-coding molecules that negatively regulate gene expression and thereby play several important roles in living organisms. Dozens of computational methods for miRNA-related research have been developed, which greatly differ in various aspects. The substantial availability of difficult-to-compare approaches makes it challenging for the user to select a proper tool and prompts the need for a solution that will collect and categorize all the methods. Here, we present tools4miRs, the first platform that gathers currently more than 160 methods for broadly defined miRNA analysis. The collected tools are classified into several general and more detailed categories in which the users can additionally filter the available methods according to their specific research needs, capabilities and preferences. Tools4miRs is also a web-based target prediction meta-server that incorporates user-designated target prediction methods into the analysis of user-provided data. Availability and Implementation: Tools4miRs is implemented in Python using Django and is freely available at tools4mirs.org. Contact: piotr@ibb.waw.pl Supplementary information: Supplementary data are available at Bioinformatics online. Oxford University Press 2016-09-01 2016-04-08 /pmc/articles/PMC5013900/ /pubmed/27153626 http://dx.doi.org/10.1093/bioinformatics/btw189 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Lukasik, Anna
Wójcikowski, Maciej
Zielenkiewicz, Piotr
Tools4miRs – one place to gather all the tools for miRNA analysis
title Tools4miRs – one place to gather all the tools for miRNA analysis
title_full Tools4miRs – one place to gather all the tools for miRNA analysis
title_fullStr Tools4miRs – one place to gather all the tools for miRNA analysis
title_full_unstemmed Tools4miRs – one place to gather all the tools for miRNA analysis
title_short Tools4miRs – one place to gather all the tools for miRNA analysis
title_sort tools4mirs – one place to gather all the tools for mirna analysis
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013900/
https://www.ncbi.nlm.nih.gov/pubmed/27153626
http://dx.doi.org/10.1093/bioinformatics/btw189
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