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seqlm: an MDL based method for identifying differentially methylated regions in high density methylation array data

Motivation: One of the main goals of large scale methylation studies is to detect differentially methylated loci. One way is to approach this problem sitewise, i.e. to find differentially methylated positions (DMPs). However, it has been shown that methylation is regulated in longer genomic regions....

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Detalles Bibliográficos
Autores principales: Kolde, Raivo, Märtens, Kaspar, Lokk, Kaie, Laur, Sven, Vilo, Jaak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013909/
https://www.ncbi.nlm.nih.gov/pubmed/27187204
http://dx.doi.org/10.1093/bioinformatics/btw304