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Modelling modal gating of ion channels with hierarchical Markov models

Many ion channels spontaneously switch between different levels of activity. Although this behaviour known as modal gating has been observed for a long time it is currently not well understood. Despite the fact that appropriately representing activity changes is essential for accurately capturing ti...

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Detalles Bibliográficos
Autores principales: Siekmann, Ivo, Fackrell, Mark, Crampin, Edmund J., Taylor, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014102/
https://www.ncbi.nlm.nih.gov/pubmed/27616917
http://dx.doi.org/10.1098/rspa.2016.0122

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