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Modelling modal gating of ion channels with hierarchical Markov models
Many ion channels spontaneously switch between different levels of activity. Although this behaviour known as modal gating has been observed for a long time it is currently not well understood. Despite the fact that appropriately representing activity changes is essential for accurately capturing ti...
Autores principales: | Siekmann, Ivo, Fackrell, Mark, Crampin, Edmund J., Taylor, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014102/ https://www.ncbi.nlm.nih.gov/pubmed/27616917 http://dx.doi.org/10.1098/rspa.2016.0122 |
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